韩春春 更新日期:2019/5/20
韩春春,女,1980年出生,博士导师
工作单位 动物遗传育种研究所
单位电话 18783580359
电子邮箱 chunchunhai_510@163.com;472930822@qq.com
招生专业 博士:090501动物遗传育种与繁殖,学硕:090501动物遗传育种与繁殖,专硕:095133畜牧
◆个人简历
韩春春,女,1980年9月生,博士,教授,博士生导师。2000-2004年在四川农业大学攻读动物科学专业获学士学位,2004-2010年于四川农业大学动物遗传育种与繁殖专业硕博连读,获农学博士学位;2009年曾赴美国康奈尔大学动物科学专业进修一年;2012年曾受邀赴法国图卢兹大学访问一个月;主要从事水禽遗传育种与分子遗传的研究,主持国家自然科学基金面上项目1项、国家自然科学青年基金1项、博士点基金新教师类1项;参加国家863计划、国家科技支撑计划等多项;以第一作者或通讯作者发表文章30多篇,其中SCI收录20篇;申请发明专利4项,实用新型1项;作为副主编《鹅标准化规模养殖图册》;作为主持人通过成果鉴定一项;作为主研参与培育的天府肉鹅配套系通过了国家品种审定;曾荣获四川省科技进步一等奖1项,四川省科技进步二等奖1项。
◆工作经历
2010.6-2010.12 四川农业大学动物科技学院 讲师
2011.1-2017.11 四川农业大学动物科技学院 副研究员
2017.12至今 四川农业大学动物科技学院 教授
◆教育经历
2000-2004年在四川农业大学攻读动物科学专业获学士学位;
2004-2010年于四川农业大学动物遗传育种与繁殖专业硕博连读,获农学博士学位;
2008-2009年于美国康奈尔大学动物科学专业联合培养博士一年。
◆获奖荣誉
2014年遴选为四川省学术和技术带头人后备人选
◆社会、学会及学术兼职
“三区”科技人才;中国畜牧兽医学会会员;四川省家禽学会理事
◆研究领域
水禽遗传育种,水禽肥肝高效安全生产及其遗传机制
◆科研项目
1、葡萄糖、果糖及蔗糖诱导鹅肝脂质沉积的差异与调控机制研究,国家自然科学基金面上项目, 2017.1-2020.12,在研,主持
2、PI3K_AKT_mTORC1信号途径在鹅肝细胞脂质代谢中的调控研究 ,国家自然科学基金青年基金项目, 2014.12,结题,主持
3、PI3K_AKT_mTORC1信号途径在鹅肝细胞生长增殖中的调控研究 ,博士点基金青年教师项目,2014.12,结题,主持
4、鹅颗粒细胞脂肪酸合成对卵泡发育的影响及作用机制研究,国家自然科学基金面上项目, 2017.1-2020.12,在研,主研
◆发表论文
第一作者和通讯作者主要论文
(1) Insulin stimulates gooseliver cell growth by activating PI3K-AKT-mTOR signal pathway. Cell Physiol Biochem. 2016,38:558-570.
(2) The Regulation of lipid deposition by insulin in goose liver cells is mediated by the PI3KAKT-mTOR signaling pathway. Plos ONE. 2015,10: e0098759.
(3) Role of mammalian sirtuin1 (SIRT1) in lipids metabolism and cell proliferation of goose primary hepatocytes. Molecular and Cellular Endocrinology, 2014,382: 282-291.
(4) Effect of cholesterol on lipogenesis and VLDL-TG assembly and secretion in goose primary hepatocytes. Mol Cell Biochem. 2013,374:163-172.
(5)Glucose-induced lipid deposition in goose primary hepatocytes is dependent on the PI3K-Akt-mTOR signaling pathway. Archives of Biological Sciences, 2016,68(4): 853-861.
(6) Change of the mTOR Pathway in Tissues of Overfed Geese. BRAZILIAN JOURNAL OF POULTRY SCIENCE. 2015,17: 293-300
(7) Effects of inhibiting PI3K-Akt-mTOR pathway on lipid metabolism homeostasis in goose primary hepatocytes. Animal. 2016, 10: 1319-1327.
(8) Inhibition of PI3K-Akt-mTOR signal pathway dismissed the stimulation of glucose on goose liver cell growth. Journal of Animal Physiology and Animal Nutrition. 2017,101:e133-e143
(9) Research progress on the importance of incubation temperature for duck egg hatching and poultry production. Worlds Poultry Science Journal. 2016,72:847-852
(10)PI3K-Akt-mTOR signal inhibition affects expression of genes related to endoplasmic reticulum stress. Genet Mol Res 2016,15: doi: 10.4238/gmr.15037868.
(11)Insulin Promotes the Expression of the Gluconeogenic Rate-Limiting Enzymes Phosphoenolpyruvate Carboxykinase (Pepck) and Glucose 6-Phosphatase (G6pase) through PI3k/Akt/mTOR Signaling Pathway in Goose Hepatocytes. BRAZILIAN JOURNAL OF POULTRY SCIENCE. 2016,18:395-400.
(12)Effect of a synthetic Liver X receptor agonist TO901317 on intracellular cholesterol concentration in goose primary hepatocytes. Italian Journal of Animal Science.2014,13:130-135.
(13) Effect of cholesterol on lipogenesis and VLDL-TG assembly and secretion in goose primary hepatocytes. Mol Cell Biochem. 2013,374(1-2):163-72.
(14) Effect of liver X receptor activation on the very low density lipoprotein secretion and messenger ribonucleic acid level of related genes in goose primary hepatocytes. Poultry Science, 2011,90 :402-409.
(15)Analysis of mRNA expression of genes related to fatty acids synthesis in goose fatty liver. Italian Journal of Animal Science.2010.9:435-438.
(16) Tissue distribution of lipoprotein lipase (LPL) and regulation of LPL gene expression induced by insulin and glucose in goose primary hepatocytes. The Journal of Poultry Science, 2010,47:139-143.
(17) The role of insulin and glucose in goose primary hepatocyte triglyceride accumulation. The Journal of Experimental Biology, 2009,212, 1553-1558.
(18)The role of LXRα in goose primary hepatocyte lipogenesis. Molecular and Cellular Biochemistry, 2009,322:37-42.
(19)Molecular cloning and gene expression of two vldlr isoforms in goose. Canadian Journal of Animal Science, 2009,89(4):441-448.
(20) Effect of Overfeeding on Plasma Parameters and mRNA Expression of Genes Associated with Hepatic Lipogenesis in Geese. Asia-aust J anim Sci ,2008,21:590-595.
◆专著教材
鹅标准化规模养殖图册(专著),中国农业出版社,2013.01出版,副主编
◆指导学生
已指导毕业研究生3届4人,协助团队指导博士生两届2人,硕士生6届8人。
◆我的团队
所属水禽团队,博士生导师3人,硕士生导师8人。