曾宪垠 更新日期:2019/5/7 1
曾宪垠,男,1966年出生,博士导师
工作单位 生命科学学院
行政职务 四川农业大学生命科学学院院长
单位电话 0835-2886138
电子邮箱 xyzeng1966@163.com 或 xyzeng@sicau.edu.cn
招生专业 博士:071011生物物理学,学硕:071011生物物理学,专硕:086000生物与医药
◆个人简历
曾宪垠,男,教授(二级),荷兰Utrecht大学博士,博士生导师,享受国务院政府特殊津贴专家,四川省学术和技术带头人,现任四川农业大学生命科学学院院长。
1966年出生于江西省瑞金市;1986年毕业于江西农业大学牧医系畜牧专业,获农学学士学位。1989年毕业于四川农业大学农业生物物理专业,获硕士学位。2002年2月于荷兰Utrecht大学获“动物生产与动物免疫调控”专业博士学位。
1989年7月至今,在四川农业大学从事“生物物理与动物生殖免疫调控”的教学和科研工作,现已在Reprod. Dom. Anim.;Anim. Reprod. Sci.; Theriogenology;J. of Anim. Sci.和Livest. Prod. Sci等国际知名杂志、国际原子能机构(IAEA)出版的专著和国内重要核心期刊上发表论文120余篇,其中SCI收录论文70余篇。
◆工作经历
1989,07 - 至今:四川农业大学从事“农业生物物理”有关教学和科研工作。
1989,07 - 1991,12: 助教。
1992,01 - 1996,12:讲师。
1997,01 - 2002,12:副教授。
2003,01 - 至今:教授。
◆教育经历
1998,03 - 2002,02:荷兰乌特列之大学(Utrecht University)与荷兰动物科学与保健研究所(ID-Lelystad)博士研究,2002年2月28日获博士学位.
1986,09 - 1989,07: 四川农业大学"农业生物物理"专业硕士研究生,1989年7月获硕士学位.
1982,09 - 1986,07:江西农业大学牧医系"畜牧"专业,于1986年7月获学士学位。
1972,09 - 1982,07:江西省瑞金市上小学、初中及高中。
◆获奖荣誉
享受国务院政府特殊津贴专家
四川省学术和技术带头人
◆社会、学会及学术兼职
四川省第三届专家评议(审)委员会委员
中国畜牧兽医学会繁殖学分会理事
中国原子能农学会理事
四川省原子能农学会副理事长
◆研究领域
动物生殖内分泌;动物生殖免疫调控。
◆科研项目
主持/主研科研项目: 1:《应用核技术提高山羊繁殖率》;国际原子能机构(IAEA)研究合同(Research Contract);1987-1989年;主研。 2:《应用免疫分析技术加强亚洲动物疾病诊断的研究》;国际原子能机构(IAEA)研究合同(Research Contract);1989-1993年;主研。 3;《应用核技术及相关技术提高家畜繁殖率》;国际原子能机构(IAEA)技术援助项目(TCP:Technical Cooperation Project);1992-1994年;主研。 4:
◆发表论文
近5年发表的部分SCI收录论文:
1)Astragalus polysaccharides enhance immune response of HBV DNA vaccination via promoting the dendritic cell maturation and suppressing Treg frequency in Mice. International Immunopharmacology, 2012, (14):463-470. Xiaogang Du, Bing Zhao, Jinao Lib, Xiaohan Cao, Mingkun Diao, Haibo Feng, Xiaobing Chen, Zhiyu Chen, Xianyin Zeng*.
2) Theoretical study on the aminolysis of p-substituted phenyl acetates with dimeric ammonia in vacuo and acetonotrile. Computational and Theoretical Chemistry, 2013, (1008), 8-14. Hanbin Rao*, Yanying Wang, Xianyin Zeng, Ying Xue, Zerong Li*.
3)Enhancement of the immuno responses to foot-and-mouth disease vaccination in Mice by oral administration of a Nonel polysaccharide from the roots of Radix Cyathulae offocinalis Kuan (RC). Cellular Immunology, 2013, (281): 111-121. Haibo Feng, Xiaogang Du, Jing Tang, Xiaohan. Cao, Xingfa. Han, Zhiyu Cheng, Yanger Chen, Xianyin Zeng*
4)Enhancement of the immune responses to ovalbumin in mice by oral administration of the extract from Radix Cyathulae (RC)。Journal of Medicinal Plants Research, 2013, 7 (19):1272-1279. Haibo Feng , Xiaogang Du , Xiaohan Cao, Zhenhua Wang , Jing Tang , Juan Liu,Bing Zhao, Zhiyu Chen, Xianyin Zeng*.
5)Active immunization against GnRH reduces the synthesis of GnRH in male rats.. Theriogenology,2013,(80):1109-1116. Xing-fa Han, Xiao-han Cao, Jing Tang, Xiao-gang Du, Xian-yin Zeng*
6) Mucosal and systemic immunity in mice after intranasal immunization with recombinant Lactococcus lactis expressing ORF6 of PRRSV. Cellular Immunology, 2014, (287) : 69-73. Zhen-hua Wang Xiao-han Cao, Xiao-gang Du, Hai-bo Feng Di –Wang, He –Song,, Xian-yin Zeng *。
7)Pharmacokinetics of PEGylated Recombinant Human Erythropoietin in Rats.Journal of Analytical Methods in Chemistry. 2014,1:1-6 .Xiaohan Cao, Zhiyong Chen, Zhuoran Yu, Yonghong Ge and Xianyin Zeng*
8)Novel polysaccharide from Radix Cyathulae Officinalis Kuan can improve immune response toovalbumin in mice. International Journal of Biological Macromolecules. 2014, 65: 121-128. Feng Haibo, Du Xiaogang, Liu Juan, Han Xingfa., Cao Xiaohan, ZengXianyin*.
9)Construction and expression of a heterologous protein in Lactococcus lactis by using the nisin-controlled gene expression system: the case of the PRRSV ORF6 gene. Genetics and Molecular Research. 2014,13(1):1088-1096. Z.H. Wang, Y.L.wang and X.Y. Zeng*.
10)Active immunization against pregnenolone reduces testicular steroidogenesis and GnRH synthesis in male rabbits. Animal reproduction science, 2014, 145(3-4):161-169. Xingfa Han, Wei Cheng, Zhiyu Chen, Xiaogang Du, Xiaohan Cao, Xianyin Zeng*.
11) Initiation of Active immunization against testosterone during early puberty alters negative feedback regulation of the hypothalamic-pituitary-testicular axis in rabbits. Domestic Animal Endocrinology, 2014 ,48:126-135. X. F.Han, W. Cheng, Z. Y. Chen, X. G. Du, X.H. Cao, X. Y. Zeng*.
12) Characterization and antioxidant activities of the polysaccharides from Radix Cyathulae officinalis Kuan. International Journal of Biological Marcromolecules, 2015, 72:544-552. Xingfa Han, Shian Shen, Tieqiu Liu, Xiaogang Du, Xiaohan Cao, Haibo Feng, Xianyin Zeng*.
13)Effect of immunization against GnRH on hypothalamic and testicular function in rams. Theriogenology, 2015,83:642-649。Han X, Gu L, Xia C, Feng J, Cao X, Du X, Zeng X*, Song T*.
14) Establishment of a Lateral Flow Colloidal Gold imunoassay Strip for the Rapid Detection of Estradiol in milk samples. LWT – Food Science and Technology, 2015, 64: 88-94. Xing-dong Yang, Fang-yu Wang, Chun-mei Song,Shu-yan Wu,Gai-ping Zhang*, Xian-yin Zeng*.
15) Development of a colloidal gold-based strip test for the detection of Chlorothalonil Residues in Cucumber. Food and Agricultural Immunology, 2015, 26 (5) :729-737。 Xing-dong Yang, Gai-ping Zhang*, Fang-yu Wang, Yinbiao Wang, Xiaofei Hu, Qingmei Liu, Guochao Jia, Zhen Liu, Yao Wang, Ruigang Deng & Xian-yin Zeng *.
16)Active immunization with GnRH-tandem-dimer peptide in young male rats reduces serum reproductive hormone concentrations, testicular development and spermatogenesis。Asian Journal of Andrology, 2016, 18(3): 485-491。Xing-fa Han, Jun-Li Li, Yu-qin Zhou, Xiao-hua Ren, Gong-cheng Liu, Xiao-han Cao, Xiao-gang Du, Xian-yin Zeng*
17)Insulin Stimulates Goose Liver Cell Growth by Activating PI3K-AKT-mTOR Signal Pathway. Cellular Physiology and Chemistry, 2016, 38:558-570. Chunchun Han*, Shouhai Wei, Qi Song, Fang He, Xiangping Xiong, Huofu Wan, Dandan Liu, Fengjiang Ye, Hehe Liu, Liang Li, Hongyong Xu, Xiaohui Du, Bo Kang, Xianyin Zeng
18)Surgical castration but not immuncastration is associated with reduced hypothalamic GnIH and GHRH/GH/IGF-I axis function in male rat. Theriogenology, 2016,86: 657-665. Han XF, Li JL, Cao XH, Du XG,, Meng FY, Zeng XY*.
19)Physiological interactions between the hypothalamic – pituitary - gonadal axis and spleen in rams actively immunized against GnRH. International Immunopharmacology, 2016, 38(c): 275-283. Xingfa Han, Xiaohua Ren, Yu Zeng, Yuqin Zhou, TianZeng Song, Xiaohan Cao, Xiaogang Du, Fengyan Meng, Yao Tan, Yacheng, Liu, Jing Feng, Mingxing Chu, Xianyin Zeng*
20) Inhibition of PI3K-AKt-mTOR signal pathway dismissed the stimulation of glucose on goose liver growth. Journal of Animal Physiology and Animal Nutrition. 2016, 20(11) :1-11. S. Wei, C. Han, F. He, Q. Song, B. Kang, H. Liu, L. Li, H. Xu and X. Zeng*
21) Improved development by melatonin treatment after vitrification of mouse metaphase II oocytes. Cryobiology. 2016, 73:335-342. Yue Zhang, Wei Li, Yongshun Ma, Dian Wang, Xiaoxue Zhao, Changjun Zeng, Ming Zhang, Xiangyin Zeng, Qinggang Meng and Guangbin Zhou*.
22) Research progress on the importance of incubation temperature for duck egg hatching and poultry production. World’s Poultry Science Journal. 2016, 72:847-852. S. WEI, X. ZENG*, C. HAN*, H. LIU, L. LI and H. XU
23)Effects of active immunization against GnRH versus surgical castration on hypothalamic-pituitary function in Boars.Theriogenology. 2017, 97:89-97. Xingfa Han, Yuqin Zhou, Yu Zeng, Fenfen Sui, Yacheng Liu, Yao Tan, Xiaohan Cao, Xiaogang Du, Fengyan Meng, Xianyin Zeng*
24) Peptides from Colochirus robustus Enhance Immune Function via Activating CD3?- and ZAP-70-Mediated Signaling in C57BL/6 Mice. International Journal of Molecular Science. 2017, 18(10): 2110 (1-15). Xiaogang Du, FangLiang Lian, Yunkun Li, Dayong Wu, Qunli Feng, Zhijiang Feng, Yun Li, Fengyan Meng, Xiaohan Cao, Zhiyu Chen and Xianyin Zeng*
25)Teleost-specific TLR25 identified from Schizothorax prenanti may recognize bacterial/viral components and activate NF-κB and type I IFN signaling pathways. Fish and Shellfish Immunology. 2018, 82,361-370. Yunkun Li , Jiayu Wu , Dong Li , Anqi Huang , Guixian Bu , Fengyan Meng, Fanli Kong, Xiaohan Cao, Xingfa Han, Xiaofu Pan, Wei fan, Shiyong Yang, Jun Wang, Xianyin Zeng *, Xiaogang Du *
26)Transcriptome analysis of spleen reveals the signal transduction of toll-like receptors after Aeromonas hydrophila infection in Schizothorax prenanti. Fish and Shellfish Immunology.,2019, 84, 816-824. Yunkun Li, Jiayu Wu, Dong Li, Anqi Huang, Guixian Bu, Fengyan Meng, Fanli Kong, Xiaohan Cao, Xingfa Han, Xiaofu Pan, Wei fan, Shiyong Yang, Xianyin Zeng*, Xiaogang Du*
27)Mechanistic insight into the role of immunocastration on eliminating skatole in boars. Theriogenology., 2019, 131,32-40 . Xingfa Han, Min Zhou, Xiaohan Cao, Xiaogang Du, Fengyan Meng, Guixian Bu, Fanli Kong, Anqi Huang, Xianyin Zeng*
◆专著教材
“Immunocastration of pigs in relation to breed, nutrition and sex: possible application in China”全英文博士论著一部,10余万字。
◆教学活动
为本科生主讲《免疫分析技术》;为博士研究生主讲《生物物理研究进展》课程;负责生物物理专业研究生的Seminar。
◆指导学生
指导已毕业博士8名,硕士41名,在读博士3名,硕士6名。
◆我的团队
团队成员目前共有8人,分别来自荷兰Utrecht大学,日本广岛大学,四川大学,中国农业大学和四川农业大学的博士。主要聚焦于“动物分子免疫与代谢”和“动物生殖免疫调控”领域的研究。